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LACTIC ACID DEHYDROGENASE ISOENZYME IN THE PERIODIC AMPUTATED RAT INCISOR PULP

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ÃÖ±Ù¹è ( Choi Keun-Bae ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­»ýÈ­Çб³½Ç

Abstract

¹é¼­ÀÇ ÀüÄ¡¸¦ ÁÖ±âÀûÀ¸·Î ÀýÁ¦ÈÄ Ä¡¼ö³»ÀÇ LDH isoenzymeÀ» Àü±â¿µµ¿¹ýÀ¸·Î ºÐ¸®ÇÏ°í ±×ÀÇ È°¼ºµµ¸¦ ÃøÁ¤ÇÏ¿© Á¤»ó°ú ºñ±³°üÂûÇѹ٠´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù. 1. Á¤»óÄ¡¼ö³»¿¡¼­ 5°³ÀÇ LDH isoenzymeÀÇ Á¸À縦 È®ÀÎÇÏ¿´´Ù. 2. LDH È°¼ºµµ´Â ÁÖ±âÀûÀ¸·Î ÀýÁ¦ÇÑ Ä¡¾ÆÀÇ Ä¡¼ö°¡ Á¤»óÄ¡¼ö¿¡ ºñÇØ ÈξÀ Áõ°¡ÇÏ¿´´Ù. 3. Ä¡¾Æ¸¦ ÁÖ±âÀûÀ¸·Î ÀýÁ¦ÇÔÀ¸·Î½á Ä¡¼ö³» LDH isoenzymeÀÇ PatternÀ» º¯È­½Ãų ¼ö°¡ ÀÖ´Ù.

In the periodic amputated rat incisor pulp, the distribution of five isoenzymes of lactic acid dehydrogenase was evaluated and the total LDH activity was assayed. This study hs established the followings; 1) It demonstrates the existence of five distinct isoenzymes of LDH, with LDH-1 and LDH-2 predominating, in the rat incisor pulp. 2) The total LDH activity in periodically amputated rat incisor pulp is markedly increased as compared to the normal rat incisor pulp. 3) It is possible that the periodic amputation of tooth effects the pattern of LDH isoenzymes in the pulp, especially LDH-1 and LDH-2 region.

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